Relationship between body mass index and outcome of in vitro fertilization and embryo transfer cycle in patients with endometriosis
10.3969/j.issn.1673-4254.2014.03.18
- VernacularTitle:子宫内膜异位症患者体质量指数与体外受精-胚胎移植周期临床结局的关系
- Author:
Zhenhui HOU
1
;
Song QUAN
;
Weiping QIAN
;
Weihong YANG
;
Liyan XU
;
Yanpei CAO
Author Information
1. 南方医科大学南方医院妇产科生殖中心
- Keywords:
endometriosis;
in vitro fertilization-embryo transfer;
body mass index
- From:
Journal of Southern Medical University
2014;(3):379-382
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between body mass index (BMI) and clinical outsomes of in vitro fertilization and embryo transfer (IVF/ICSI-ET) cycles in patients with endometriosis. Methods We retrospectively analyzed the data of infertile women with endometriosis undergoing 244 IVF/ICSI-ET cycles between January, 2011 and August, 2012. The patients, categorized into 3 groups with mild endometriosis, moderate to severe endometriosis, and no endometriosis (control), underwent a long protocol, and the relationship of the general conditions, dose of gonadotropin, days of stimulation, BMI, number of oocytes retrieved and embryos transferred with the outcome of IVF were analyzed. Results There was significant difference between moderate to severe endometriosis group and the control group in the number of ampules, oocytes retrieved and embryos transferred. The patients with moderate or severe endometriosis had significantly lower BMI and clinical pregnancy rate than those with mild or no endometriosis. Conclusion Endometriosis is inversely correlated with BMI, and BMI of the patients with endometriosis may affect the pregnancy rate of IVF cycles.
