A Case of Primary Neuroendocrine Carcinoma of the Gallbladder Associated with Anomalous Union of the Pancreaticobiliary Duct.
- Author:
Kyoung Won YOON
1
;
Chang Hwan PARK
;
Wan Sik LEE
;
Young Eun JOO
;
Hyeun Soo KIM
;
Sung Kyu CHOI
;
Jong Sun REW
;
Jae Hyug LEE
Author Information
1. Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea. p1052ccy@hanmail.net
- Publication Type:Case Report
- Keywords:
Anomalous union;
Pancreaticobiliary duct;
Neuroendocrine tumor;
Gallbladder
- MeSH:
Bile Ducts;
Carcinoma, Neuroendocrine;
Cholangitis;
Choledocholithiasis;
Gallbladder;
Gallbladder Neoplasms;
Inflammation;
Metaplasia;
Mucous Membrane;
Neuroendocrine Cells;
Neuroendocrine Tumors;
Pancreatitis
- From:Gut and Liver
2009;3(3):231-234
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary neuroendocrine carcinoma of the gallbladder is extremely rare because normal gallbladder mucosa does not contain neuroendocrine cells. Neuroendocrine cells can be detected at sites of intestinal metaplasia induced by chronic inflammation, which may be the initial step in the development of neuroendocrine tumor of the gallbladder. Anomalous union of the pancreaticobiliary duct (AUPBD) is an uncommon congenital anomaly that is frequently associated with choledocholithiasis, cholangitis, pancreatitis, and cancer of the gallbladder or bile duct. In AUPBD, cancers of the gallbladder and bile duct can be induced by chronic inflammation. We report herein a case of large-cell neuroendocrine tumor of the gallbladder associated with AUPBD.
