Evaluation of left ventricular diastolic function by TE- e' measurement using dual Doppler echocardiography in coronary heart disease patients with preserved systolic function
10.3969/j.issn.1673-4254.2014.03.12
- VernacularTitle:双脉冲多普勒超声心动图技术测量TE-e’评估冠心病患者左心室舒张功能
- Author:
Jingjing WANG
1
;
Yundai CHEN
;
Jing WANG
;
Guang ZHI
;
Yang MU
;
Yong XU
Author Information
1. 解放军总医院心血管内科
- Keywords:
Doppler tissue imaging;
coronary heart disease;
left ventricular diastolic function;
left ventricular end-diastolic pressure;
dual Doppler echocardiography
- From:
Journal of Southern Medical University
2014;(3):349-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of the time interval between the onset of early transmitral flow velocity (E) and that of early diastolic mitral annular velocity (e') (TE- e') measured by dual Doppler echocardiography in the diagnosis of diastolic dysfunction. Methods Seventy-seven coronary heart disease patients with preserved systolic function underwent a echocardiographic study. Early transmitral flow velocity E and early diastolic mitral annular velocity e' were simultaneously recorded by dual Doppler echocardiography. The E/e' and TE-e' were calculated and compared with the left ventricular end diastolic pressure (LVEDP), which was measured invasively. The validity of TE-e', E/e' and their combination was analyzed in estimating left ventricular dysfunction (LVEDP ≥12 mmHg). Results The single-beat E/e' and TE-e' were correlated with the LVEDP (r=0.79 and 0.42, respectively, P<0.001). Receiver-operating characteristic analysis showed that the optimal cut-off for TE-e' was 38 ms (sensitivity 54%, specificity 79%, AUC 0.71) and that for E/e' was 9.2 (sensitivity 74%, specificity 81%, AUC 0.87) for diagnosis of left ventricular diastolic dysfunction. The combined cut-offs of TE-e'≥38 ms and E/e'≥9.2 had a sensitivity of 100%and a specificity of 62%in diagnosing left ventricular diastolic dysfunction with an AUC of 0.96. Conclusion In patients with coronary heart disease, the simultaneous recording of TE-e' by dual Doppler echocardiography can accurately estimate diastolic dysfunction, and its combination with E/e' can further improve the diagnostic accuracy.
