Analysis of common viral pathogen spectrum of acute respiratory infection cases in Changshu city from 2022 to 2023
10.3760/cma.j.cn112866-20240126-00015
- VernacularTitle:2022—2023年常熟市急性呼吸道感染病例常见病毒病原谱系分析
- Author:
Yake GUAN
1
;
Zhengyuan ZHOU
;
Guoyong MEI
;
Jinyi GAO
;
Haijun DU
;
Jun HAN
;
Cuiling XU
Author Information
1. 中国疾病预防控制中心病毒病预防控制所 传染病溯源预警与智能决策全国重点实验室，北京 102206
- Keywords:
Acute respiratory infection;
Virus;
Pathogenic spectrum;
Epidemiology
- From:
Chinese Journal of Experimental and Clinical Virology
2024;38(3):252-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the common viral pathogen spectrum of acute respiratory infection (ARI) cases in Changshu city.Methods:Nasopharyngeal swab samples from outpatients and inpatients in five sentinel hospitals in Changshu city from January 2022 to October 2023 were collected. Real-time fluorescent quantitative polymerase chain reaction was used to detect the nucleic acids of influenza virus (Flu) and respiratory syncytial virus (RSV), adenovirus (AdV), human rhinovirus (HRV), human parainfluenza virus (HPIV), enterovirus (EV), human coronavirus (HCoV), human metapneumovirus (HMPV), and human bocavirus (HBoV).Results:Of the 1 936 ARI cases, 18.1% (350/1 936) were tested positive for viral nucleic acid. Flu had the highest detection rate (7.1%), followed by HBoV (3.7%), AdV (1.9%) and RSV (1.6%). The virus detection rate was significantly different among different age groups and seasons. In March 2023, the total virus detection rate was the highest (47.6%), mainly Flu. Flu showed unimodal prevalence in spring and winter. The prevalence trend of HBoV and HCoV was consistent, and the detection rate of HBoV (5.43%) was higher than that of HCoV (2.45%), both of which peaked in summer. RSV prevalence peaks in autumn (4.5%). The detection rate of children aged 0-5 years was the highest, reaching 33.3%.Conclusions:The main ARI pathogens in Changshu city from 2022 to 2023 were Flu, HBoV, AdV and RSV.
