Pericardial Effusion in Patients with Lung Cancer Treated with Safe-Dwel Plus Drain and Intrapericardial Chemotherapy
10.3321/j.issn:1000-467X.2001.04.022
- VernacularTitle:中心静脉导管引流并心包内化疗治疗肺癌致心包积液
- Author:
Feng GAO
1
;
Qiu-Yan LI
;
Jian-Guo SUN
;
Shou-Zhong FU
;
Jun-Feng WANG
Author Information
1. General Hospital of Jixi Mining Bureau
- From:Chinese Journal of Cancer
2001;20(4):429-430
- CountryChina
- Language:Chinese
-
Abstract:
Objective： The aim of this study was to approach an efficient way in the treatment of pericardial effusion of lung cancer. Methods： Sixteen patients with pericardial effusion of lung cancer are drained with Safe-Dwel Tlus, then cisplatin and etoposide were injected into the pericardial cavity, and the draining continually effusion to less 50 ml per day. Results： The total effective rate was 93.8％ with 13 cases of complete response rate and 2 cases of partial response rate. The median survival time was 6.5 months. 2 cases died from the relapse of pericardial effusion or no effect. Eleven cases had gastrointestinal tract reaction, and 3 cases with repression of bone marrow. However all side effects were controlled by treatment. Conclusion： Safe-Dwel Tlus drain with injecting cisplatin and etoposide into pericardial cavity may be a better way to control malignant pericardial effusion of lung cancer.
