Short-Term Effect of Conformal Radiotherapy for Recurrent Nasopharyngeal Carcinoma
10.3321/j.issn:1000-467X.2001.02.013
- VernacularTitle:鼻咽癌局部复发适形放疗近期疗效分析
- Author:
Shao-Jun LIN
1
;
Jian-Ji PAN
;
Jun-Xin WU
;
Xiang-Song LIN
Author Information
1. Cancer Hospital of Fujian
- From:Chinese Journal of Cancer
2001;20(2):171-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective： The current study was designed to evaluate the treatment results of nasopharyngeal carcinoma by conformal radiotherapy. Methods： From September 1997 to February 2000, a total of 41 cases of recurrent nasopharyngeal carcinoma were treated by conformal radiotherapy. Among them, 27 cases were treated by late-course hypofraction conformal radiotherapy with the dose of 20- 24 Gy at 80％ isodose, 4- 7 Gy per time, following routine radiotherapy of 39 Gy/30f/3weeks. Fourteen cases received total-course conformal radiotherapy with the dose of 59.8 Gy/46f/4.6weeks at 90％ isodose. Results： The reference isodose curves conform to the target in three dimensions in conformal radiotherapy. The acute radiation mucositis, cranial nerve paralysis and trismus incidence were similar in two groups, however, in the hypofractionation group 22％ developed necrosis of nasopharyngeal mucosa, 3.7％ developed reduced optic nerve lesion, whereas none of the hyperfractionation group had these complications. The tumor response rate were both 93％ for two groups. Conclusion： Hyperfraction conformal radiotherapy is effective in the treatment of recurrent nasopharyngeal carcinoma and has relatively lower incidence of radiation complication.
