Somatostatin Receptor Subtype SSTR-2 and SSTR-3 mRNA Expression in Primary Hepatic Carcinoma
10.3321/j.issn:1000-467X.2001.02.008
- VernacularTitle:生长抑素受体亚型SSTR-2和SSTR-3mRNA在原发性肝癌中的表达
- Author:
Deng-Guo YAN
1
;
Qing-Jia OU
Author Information
1. Sun Yat-sen Memorial Hospital of Sun Yat-sen University of Medical Sciences
- From:Chinese Journal of Cancer
2001;20(2):152-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective： The current study was designed to investigate SSTR subtype gene expression in tissue of primary hepatic carcinoma. Methods： The expression of SSTR-2 and SSTR-3 mRNA in the tumor tissue of hepatic carcinoma and the adjacent tissue of cancer in 27 patients with primary hepatic carcinoma was examined by RT-PCR. Results： The positive rate of expression of SSTR-2 mRNA in the tissues of hepatic carcinoma was 81.5％ ( 22/27) , and the positive rate of expression in the adjacent tissues of cancers was 96.3％ (26/27). The positive rate of SSTR-3 mRNA in tumor tissues and the adjacent tissues of hepatic carcinoma were 66.7％ ( 18/27) and 51.9％ (14/27), respectively. Conclusion： There are more than one SSTR subtype genes expression in tumor tissues of primary hepatic carcinoma.
