Diagnostic value of ultrasonography in combination with mammography for breast cancer within 2 cm:a meta-analysis
- VernacularTitle:超声和钼靶X线联合诊断2 cm以内乳腺癌的meta分析
- Author:
Huan LIN
1
;
Hansheng LIN
;
Hong LIANG
Author Information
1. 南方医科大学第一临床医学院2009级医学影像学专业
- Keywords:
breast cancer;
ultrasonography;
mammography;
early diagnosis;
systematic review;
meta-analysis
- From:
Journal of Southern Medical University
2013;(11):1699-1703
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of ultrasonography in combination with mammography for breast cancer within 2 cm. Methods The PubMed, the Cochrane Library, CNKI, CBM and Wanfang databases (2003/01/01-2013/04/30) were searched for studies of the diagnostic value of ultrasonography in combination with mammography for breast cancer within 2 cm. The quality of the included studies was evaluated according to QUADAS items. The pooled sensitivity (SEN), pooled specificity (SPE), pooled diagnostic odds ratio (DOR), and area under summary receiver operating characteristic curve (AUC) were calculated using Review Manager 5.2 and Meta-DiSc 1.4 software. Results Nine articles were included in the final analysis. The pooled SEN of ultrasonography, mammography and their combination were 0.75, 0.66, and 0.92, the pooled SPE 0.75, 0.83, and 0.82, the pooled DOR 7.11, 8.67, and 60.82, and the AUC 0.7902, 0.8120, and 0.9469, respectively. Conclusion The combination of ultrasonography and mammography can increase the diagnostic accuracy for breast cancer within 2 cm.
