Preliminary investigation and analysis on the epidemic situation of Redondoviridae in Beijing
10.3760/cma.j.cn112866-20221025-00217
- VernacularTitle:北京市Redondoviridae流行情况初步调查与分析
- Author:
Jiachen ZHAO
1
;
Yimeng LIU
;
Lin ZOU
;
Xiaomin PENG
;
Guilan LU
;
Cheng QIAN
;
Shujuan CUI
;
Daitao ZHANG
;
Weixian SHI
Author Information
1. 北京市疾病预防控制中心，北京 100013
- Keywords:
Redondoviridae;
Epidemiological analysis;
Pathogenicity
- From:
Chinese Journal of Experimental and Clinical Virology
2023;37(2):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the epidemic situation of Redondoviridae in Beijing and analyze its epidemiologic characteristics.Methods:Pharyngeal swab samples of healthy people and patients with acute respiratory infection in Beijing, including influenza like cases and severe acute respiratory infection (SARI) cases in hospitals were collected. Real time PCR was used to detect the nucleic acid of Redondoviridae. The positive samples were amplified and sequenced to analyze their species. The age and sex distribution of patients and species distribution of Redondoviridae were obtained through statistical analysis. Multiplex PCR was used to detect other common respiratory pathogens in the positive samples of Redondoviridae in influenza like cases and SARI cases, and the pathogenicity of Redondoviridae was analyzed.Results:The positive rates of Redondoviridae in healthy people and acute respiratory infection cases were 20.48% (189/923) and 11.23% (43/390), respectively, with a statistically significant difference ( P<0.05). The positive rate of male was higher than that of female in the healthy population, and the positive rate of the elderly group was higher than that of the adult group and the underage group, with a statistically significant difference ( P<0.05). The positive rate of male patients with acute respiratory tract infection was higher than that of female patients, but there was no significant difference. The proportion of Vientovirus in the positive samples of Redondoviridae was higher than that of Brisavirus, and the difference was statistically significant ( P<0.05). Among the throat swabs of respiratory tract infection cases, 43 were positive for Redondoviridae, of whom 24 were not detected for other pathogens. Conclusions:Redondoviridae widely exists in healthy people of all age groups in Beijing, and is also found in acute respiratory infection cases. The positive rate of Redondoviridae is different in different ages and genders. Both Vientovirus and Brisavirus were detected, and the proportion of Vientovirus was significantly higher than Brisavirus.
