Comparison of dissolution properties between Ginseng micropowder and common powder
- VernacularTitle:人参超微粉与细粉的体外溶出度比较
- Author:
Lu CAI
1
;
Shaoyu LIANG
;
Kaijin DAI
;
Feijun XIANG
;
Qizhi LUO
Author Information
1. 南方医科大学 肿瘤研究所
- Keywords:
ginsenosides;
dissolution rate;
ginseng micropowder;
ginseng common powder
- From:
Journal of Southern Medical University
2013;(10):1547-1550
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the dissolution properties of Ginseng micropowder and common powder in vitro and investigate the effect of micronization on dissolution of Ginseng. Methods Five ginsenosides including Rg1, Re, Rf, Rb1, and Rb2 were determined by high performance liquid chromatography, and the dissolution curves of Ginseng micropowder and common powder were drawn. Results The dissolution rates of ginsenosides from micropowder exceeded 90%within 5 min, significantly greater than that from common powder. But when the powders were packed in tea bags, the dissolution rates of ginsenosides were higher from common powder than from micropowder. Conclusion Micronization treatments can promote dissolution of ginsenosides from Ginseng.
