Research progress in the etiology and epidemiology of enterovirus in hand, foot and mouth disease

VernacularTitle:常见手足口病肠道病毒病原学及流行病学研究进展
Author: Wei CHU ¹ ; Zheyun HUA ; Yiqun LOU ; Hongwei ZHU ; Lili SONG ; Zhiyi LING
Author Information

1. 上海市黄浦区疾病预防控制中心，上海　200023
Keywords: Hand; foot and mouth disease; Enterovirus; Etiology; Epidemiology
From: Chinese Journal of Experimental and Clinical Virology 2022;36(4):494-498
CountryChina
Language:Chinese
Abstract: Hand, foot and mouth disease (HFMD) is an acute infectious disease induced by enterovirus. More than 30 pathogenic viruses for hand, foot and mouth disease have been discovered, of which enterovirus 71 (EV-A71) and Coxsackievirus A16 (CV-A16) are the most common. Enterovirus 71 (EV-A71) is also the main cause of severe hand, foot and mouth disease. In recent years, it has been discovered that Coxsackievirus A6 (CV-A6) infection has broken out in many regions of the world, and the pathogenicity rate is increasing, which indicatesthat it may rise to become a new major pathogenic agent of hand, foot and mouth disease. Hand, foot and mouth disease has become a global public health problem. Therefore, research on the pathogenic mechanism of multiple enteroviruses that induce hand, foot and mouth disease and analysis of its epidemiology will become the top priority of prevention, control and treatment of the disease.