Advances in the molecular typing characteristics of group A rotavirus
10.3760/cma.j.cn112866-20220217-00034
- VernacularTitle:A组轮状病毒分子分型特点研究进展
- Author:
Guangping XIONG
1
;
Dandi LI
Author Information
1. 中国疾病预防控制中心病毒病预防控制所 国家卫生健康委员会医学病毒和病毒病重点实验室,北京 102206
- Keywords:
Group A rotavirus;
Genotype;
Vaccine
- From:
Chinese Journal of Experimental and Clinical Virology
2022;36(2):239-242
- CountryChina
- Language:Chinese
-
Abstract:
Group A rotavirus (RVA) is one of the most important pathogens of non-bacterial acute gastroenteritis in infants and children under 5 years of age, and diarrhea caused by RVA infection poses a huge disease burden to infants and children worldwide. The effectiveness of vaccines is closely related to RVA genotypes; therefore, this paper summarizes the recent progress in molecular typing characteristics of RVA at home and abroad to provide important information on genotypic diversity and a reference for the selection of virulent strain genotypes in current and future vaccine development.