Comparison of nucleic acid detections between throat swab and stool specimens in 2019-nCoV infected patients
10.3760/cma.j.cn112866-20200303-00041
- VernacularTitle:新型冠状病毒肺炎病例粪便及咽拭子核酸平行检测结果比对分析
- Author:
Bo LI
1
;
Hao ZHANG
;
Boan LI
;
Zhu CHEN
Author Information
1. 解放军总医院第五医学中心临床检验医学中心，北京 100039
- Keywords:
2019-nCoV;
Reverse transcriptase polymerase chain reaction;
Throat swab;
Stool
- From:
Chinese Journal of Experimental and Clinical Virology
2022;36(2):236-238
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the positive rate of nucleic acid detections in throat swab and stool specimens of patients, thereby to provide a reference to the clinical laboratory diagnosis.Methods:Forty-one confirmed patients were enrolled in this study, their throat swab and stool specimens were collected for detections. All the samples were determined by a fluorescence quantitative PCR method . The positive rate and concordance were evaluated for these two types of samples.Results:Among those 41 patients, 9 of them had positive result in throat swab samples, accounted for 30%. Five patients had positive result in stool samples, accounted for 12.2%. Only two patients had concordant positive result . Kappa tests showed that the concordance was poor, kappa index was 0.153. Conclusions:The nucleic acid detection in stool specimen is a complemental method for respiratory tract samples and therefore may provide. additional information for infectiousness of patients.
