Epidemiological characteristics and risk factors of 2019-nCoV infection in close contacts, Shandong
10.3760/cma.j.cn112866-20201111-00283
- VernacularTitle:山东省新型冠状病毒肺炎密切接触者感染流行病学特征及危险因素分析
- Author:
Shaoxia SONG
1
;
Lin SUN
;
Qing DUAN
;
Dapeng SUN
;
Shengyang ZHANG
;
Jiyu ZHANG
;
Bingqin DAI
;
Bingyin ZHANG
;
Dianmin KANG
;
Zengqiang KOU
Author Information
1. 山东省疾病预防控制中心，济南 250014
- Keywords:
2019 novel coronavirus (2019-nCoV);
Close contact;
Epidemiological characteristics;
Risk factor
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(6):700-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the infection rate of Coronavirus Disease 2019 (COVID-19) in close contacts in Shandong province and explore the risk factors of infection.Methods:All data from close contacts of 2019 novel coronavirus (2019-nCoV) infected persons in Shandong province were collected for descriptive epidemiological analysis, and risk factors were analyzed by logistic regression.Results:Up to March 6, 2020, a total of 15 702 close contacts had been reported in Shandong province, of whom 321 cases were infected with 2019-nCoV, with an infection rate of 2.04%. Among all the factors, the top five with the highest infection rate were close relatives (13.39%), frequent contact (9.58%), working/living/studying in the same room (7.54%), two or more contact cases (4.58%), and over 60 years old (3.10%). Single-factor analysis showed that exposure to two or more cases, over 60 years old, close relatives with cases, frequent contact and working/living/studying in the same room were the risk factors for infection in close contacts. Multivariate analysis showed that exposure to two or more cases ( OR=2.510, 95% CI: 1.843-3.417), 30~60 year old group ( OR=1.513, 95% CI: 1.141-2.007), frequent exposure group ( OR=20.025, 95% CI: 14.625-27.419), working/living/learning in the same room ( OR=2.406, 95% CI: 1.385-4.182) and medical institution exposure ( OR=2.366, 95% CI: 1.149-4.871) were risk factors of infection in close contacts. Conclusions:Tracking and managing close contacts was an important measure to control the COVID-19 epidemic situation, and reducing crowd concentration, keeping a proper social distance and taking effective protection were effective measures to control 2019-nCoV infection.
