Comparison of results of nucleic acid detection between anal swabs and nasal swabs in confirmed cases of COVID-19
10.3760/cma.j.cn112866-20200317-00072
- VernacularTitle:新型冠状病毒肺炎患者肛拭子和鼻拭子核酸检测结果比较分析
- Author:
Kanru CAI
1
;
Jieyun ZHANG
;
Yabo PENG
;
Qianting YANG
;
Xiuyun ZHU
;
Xunuo LIU
;
Yunjian MA
;
Mingxia ZHANG
Author Information
1. 深圳市第三人民医院肝病研究所 518000
- Keywords:
COVID-19;
Anal swabs;
Nasal swabs;
Nucleic acid
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(6):655-657
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the result of nucleic acid detection between anal swabs and nasal swabs in confirmed cases of COVID-19.Methods:The result of nucleic acid detection between anal swabs and nasal swabs collected simultaneously at various time points after illness onset were analyzed retrospectively.Results:Totally, 46 matched result of anal swabs and nasal swabs in confirmed cases of COVID-19 collected at various intervals after illness onset in 31 patients were analyzed. All the result of nucleic acid detection were positive for anal swabs. The highest concordance rate of nucleic acid positive of COVID-19 (80%) between anal swabs and nasal swabs was observed 0-3 days after illness onset; while the value declined to 28.57% ≥16 days after illness onset. The longer the interval between sampling and illness onset, the lower the concordance rate.Conclusions:Besides two negative result from respiratory tract specimens, the negative result of anal swabs should be added as an important reference of releasing from quarantine.
