Research progress of novel coronavirus reference materials
10.3760/cma.j.cn112866-20210714-00124
- VernacularTitle:新型冠状病毒标准物质研究进展
- Author:
Ying GAO
1
;
Yi YANG
;
Yanyan OUYANG
;
Wei MI
;
Lianhua DONG
;
Xinhua DAI
Author Information
1. 中国计量科学研究院，北京 100029
- Keywords:
Novel coronavirus;
Reference materials;
in vitro Transcribed RNA;
Inactivated virus;
Pseudovirus;
Monoclonal Aantibody;
Nucleic acid test;
Serological test
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(5):590-595
- CountryChina
- Language:Chinese
-
Abstract:
The reference material (RM) of novel coronavirus (2019n-CoV) is a kind of sufficiently homogeneous and stable material including determined 2019n-CoV sequence and quantity information. The international and domestic RM includes in vitro transcribed and genomic RNA RM, pseudovirus and inactivated virus RM, and protein RM. It can be used as a "ruler" for traceability and method validation of testing agent, performance evaluation of 2019n-CoV testing kits, and laboratory proficiency testing. It also can be used as quality control material to ensure accuracy of tests. Furthermore, RMs of 2019n-CoV plays an important role in the international equivalence and international mutual recognition about 2019n-CoV testing.
