Epidemiological characteristics of viral agents in 1 092 children with acute lower respiratory diseases in Changsha
10.3760/cma.j.cn112866-20210519-00080
- VernacularTitle:长沙1 092例急性下呼吸道疾病患儿病毒感染的流行病学特征分析
- Author:
Jieying ZHOU
1
;
Yaping SUN
;
Yingbiao LIN
;
Zhaojun DUAN
;
Youde CAO
;
Zhiping XIE
Author Information
1. 郴州市第一人民医院 423000
- Keywords:
Real-time fluorescent quantitative PCR;
Respiratory virus;
Epidemiology
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(4):433-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the pathogenic spectrum and epidemiological characteristics of respiratory viruses in children with acute lower respiratory tract infection in Changsha, and provide scientific basis for disease prevention and treatment.Methods:A total of 1 092 respiratory tract specimens of children were collected and 12 respiratory viruses were detected by real-time quantitative transcription polymerase chain reaction.Results:Among the samples from 1 092 cases, those from 437 cases (40%) were positive for respiratory syncytial virus (RSV), 337 cases (30.9%) were positive for parainfluenza virus-3 (PIV-3), 263 cases (24.1%) were positive for human bocavirus (HBOV) and 228 cases (20.8%) were positive for adenovirus (ADV). The detection rates of boys and girls were 82.26% and 83.42%. The infection rate of RSV was higher in the group ≤ 6 months of age, the infection rates of PIV-3 and HBOV ≤2 years old were higher, and the infection rate of ADV was higher in the group between 6 months to 5 years old. The detection rates of virus infection of spring, summer, autumn and winter were 90.48%, 83.50%, 62.26% and 82.80%, respectively, there were significant differences among them.Conclusions:The main viruses in children with acute lower respiratory tract infection in Changsha were RSV and PIV-3. Mixed infections were common. Children under 2 years of age were more likely to get acute lower respiratory infections. Viruses had seasonal trends and peaked in winter and spring.
