Retesting of HIV antibody positive samples and analysis of confirmatory results
10.3760/cma.j.cn112866-20201103-00277
- VernacularTitle:HIV抗体初复检反应性样本再复检及确证结果分析
- Author:
Jialu YAN
1
;
Jing TONG
;
Yangguang DU
;
Yadi GUAN
Author Information
1. 浙江省东阳市疾病预防控制中心 322100
- Keywords:
HIV;
HIV antibody test;
Confirmatory test
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(4):404-407
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the coincidence rate between the initial test and the retest result of the laboratory, and the relationship between the result of reexamination and the result of confirmation by analyzing the retesting and confirmatory result of positive samples in various medical institutions,Methods:A total of 710 HIV antibody positive samples from medical institutions within the jurisdiction of Xuzhou city from January 1 to December 31, 2018 were retrospectively collected as research materials. The source, population, reinspection result and confirmatory result were analyzed respectively.Results:The positive rate of reexamination in medical institutions, disease control institutions and blood collection and supply institutions was 62.12%(269/433), 96.53%(167/173), 14.42%(15/104), respectively. The double-reactive samples were confirmed to be positive at the time of reexamination or follow-up. The inconsistencies in the reexamination result were confirmed to be negative by the appropriate time or follow-up. The false positive rate by Bio-Rad reagents was 0.23% (1/443), the false positive rate by Alere reagents was 1.78% (8/450).Conclusions:From high to low, the retest compliance rate was in the order of disease control institutions, medical institutions, blood collection and supply institutions. The samples sent by the CDC can be tested directly without retesting. Therefore, the double-reactive samples in the reinspection should be mainly followed up. If the retest result are inconsistent and the samples are not confirmed positive or the follow-up result are positive, there is no missing test. The specificity of Bio-Rad reagents is better than that of Alere reagents.
