Factors influencing the results of 2019-nCoV nucleic acid test
10.3760/cma.j.cn112866-20200520-00169
- VernacularTitle:新型冠状病毒核酸检测结果的影响因素
- Author:
Yujia HUO
1
;
Lifeng PAN
;
Qiqi CUI
;
Qing LIU
;
Yang YUAN
;
Lipeng HAO
Author Information
1. 上海市浦东新区疾病预防控制中心 200136
- Keywords:
COVID-19;
2019-nCoV;
Nucleic acid test
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(3):345-348
- CountryChina
- Language:Chinese
-
Abstract:
Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by 2019 novel Coronavirus (2019-nCoV). At present, the most used method to diagnose 2019-nCoV is nucleic acid test. Suspected cases underwent real-time fluorescent RT-PCR examination, and those who were 2019-nCoV nucleic acid positive were confirmed cases. However, in the process of nucleic acid test, factors such as specimen quality, specimen transportation and storage conditions, detection reagents and methods may cause false negative or false positive results. This article reviews the factors that may affect the results of 2019-nCoV nucleic acid test, and provides a basis for the diagnosis of suspected COVID-19 cases.