Immunohistochemical study of interleukin-8 in human nasal polyps

VernacularTitle:白细胞介素-8在鼻息肉中的免疫组化研究
Author: Ai-Xin HUANG ¹ ; Xiang-Ping LI
Author Information

1. Nanfang Hospital First Military Medical University
Keywords: interleukin-8; nasal polyp; immunohistochemistry
From: Journal of Southern Medical University 2000;20(6):521-522
CountryChina
Language:Chinese
Abstract: Objective To investigate the distribution and expression of immunoreactive interleukin-8 (IL-8) in the human nasal polyps. Methods Thirty-two specimens of nasal polyp and 12 specimens of normal inferior turbinate were studied with immunohistochemistry SABC method. Results IL-8 antigen staining was observed predominantly in the acidophilic and the epithelium cells in the nasal polyps, and immunoreactive IL-8 was distributed widely in the cell plasm of these cells, and IL-8 antigen staining was barely observed in control. Conclusion IL-8 may play a significant role in the pathogenesis of nasal polyps.