The results of proficiency test of HIV-1 viral load testing laboratories in China from 2005 to 2019
10.3760/cma.j.cn112866-20210120-00012
- VernacularTitle:2005—2019年我国HIV-1病毒载量检测实验室能力验证考核结果分析
- Author:
Yunpeng XUE
1
;
Xin ZHANG
;
Qiyu ZHU
;
Jing LIU
;
Xiaoxia TAO
;
Huazhou JIANG
;
Ling ZHANG
;
Yan JIANG
;
Cong JIN
;
Pinliang PAN
Author Information
1. 中国疾病预防控制中心性病艾滋病预防控制中心参比实验室，北京 102206
- Keywords:
HIV-1;
Viral load;
Proficiency testing
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(2):135-139
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the testing capacity of HIV-1 viral load testing laboratories, and to provide data references for further improving the accuracy of laboratory test result in China.Methods:The test result of 155 positive samples distributed by the National AIDS Reference Laboratory to each laboratory from 2005 to 2019 were summarized and grouped according to the test assay and sample number. The independent sample t-test was used to evaluate the economic status and the proficiency testing (PT) assessment period on the stability of the test results. And, one-way analysis of variance was used to evaluate the influence of the types of laboratories and reagents on the stability of test results.Results:The number of HIV-1 viral load testing laboratories increased from 13 in 2005 to 267 in 2019. The participating institutions were mainly centers for disease control and prevention(CDC)and hospitals. Since 2015, the excellent rate of laboratories has remained above 85%, and the unqualified rate has remained below 3%. The associated factor analysis showed that the laboratory testing stability of HIV-1 viral load associated with the PT assessment period and the types of testing reagents, and the laboratories participating in the PT assessment for more than 5 years showed better stability.Conclusions:Participating in the annual proficiency testing program helped improve the laboratory capability of HIV-1 viral load testing in China.
