Epidemiological and clinical characteristics of seven children with Coronavirus Disease 2019
10.3760/cma.j.cn112866-20200326-00093
- VernacularTitle:7例儿童新型冠状病毒肺炎病例的临床特征
- Author:
Yu CHEN
1
;
Liang SHEN
;
Chunhua WANG
;
Rui PAN
;
YongChao JIANG
Author Information
1. 湖北文理学院附属医院 襄阳市中心医院，襄阳 441021
- Keywords:
Children;
COVID-19;
Epidemiology;
Clinical characteristics
- From:
Chinese Journal of Experimental and Clinical Virology
2021;35(1):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Retrospective analysis of the epidemiological and clinical characteristics of the novel coronavirus pneumonia (COVID-19) in children, to provide suggestions for the clinical diagnosis and treatment of children infected with SARS-CoV-2.Methods:7 COVID-19 children admitted to Xiangyang Central Hospital from January to February 2020 were studied. The epidemiological, clinical, laboratory, radiological characteristics and disease outcome data were obtained from data collection forms and electronic medical records.Results:Among the 7 children, 3 were male and 4 were female, median age was 8 years (2.6-14.0), 2 patients with co-morbidities , 4 patients with family aggregation history, two of them are brothers and sisters, all of the 7 children had a history of high-risk epidemiology. The main clinical symptoms of children with COVID-19 were fever (4 cases), cough and expectoration (5 cases), whereas others were asymptomatic (2 cases). The peripheral blood manifestations of the patients were as follows: abnormal leukocyte count was observed in 1 case, decrease of neutrophil was observed in 2 cases , 1 case with increase of C-reactive protein (CRP) and 3 cases with increase of lactate dehydrogenase, other indexes like the lymphocyte count was normal in all patients. There were no significant changes in serum albumin, AST, CK and SCR in children. Most of the chest CT findings of children were high density lesions of lung lobes, 2 of them had typical ground glass density shadow. The clinical types of 5 children were common type and the rest are subclinical type. All cases were cured by antiviral plus symptomatic treatment(Arbidol), and combination of traditional Chinese medicine prescription treatment.Conclusion:Children COVID-19 were mainly mild and common cases, most of them were familial clusters, the laboratory examination showed no specificity and their prognosis was well.
