Research progress in noncoding RNA involved in regulating innate antiviral immunity against influenza A virus

VernacularTitle:非编码RNA调控抗甲型流感病毒天然免疫应答的研究进展
Author: Xiuhua YU ¹ ; Yang GAO ; Cheng LU ; Huanji CHENG
Author Information

1. 吉林大学第一医院小儿呼吸一科，长春　130021
Keywords: Non-coding RNA; Influenza A virus; Innate immune response
From: Chinese Journal of Experimental and Clinical Virology 2020;34(6):665-670
CountryChina
Language:Chinese
Abstract: Non-coding RNA (ncRNA) have enormous regulatory functions and play important roles in a variety of cellular processes including cell growth, differentiation, survival and apoptosis. Influenza A virus (FluA) is an important pathogen of serious threats to human health and livestock industry. The interaction mechanism between FluA and the host is very complicated. FluA infection can lead to differential expression of hundreds of host ncRNA, which has become a research hotspot in life sciences in recent years. This review summarizes the progress in different host-encoded ncRNA involved in regulating FluA infection, not only to study the interaction between viruses and hosts, but also to discover new antiviral strategies.