The epidemiological characteristics and clinical diagnosis and treatment of 43 cases of novel coronavirus pneumonia
10.3760/cma.j.cn112866-20200908-00237
- VernacularTitle:43例新型冠状病毒肺炎流行病学特点及临床诊治分析
- Author:
Jian ZHANG
1
;
Yunhong ZHAO
;
Yingxin HUANG
;
Lina FENG
;
Fei TENG
;
Ying ZHANG
;
Weina PAN
;
Wenyu CUI
Author Information
1. 长春市传染病医院 130123
- Keywords:
COVID-19;
Epidemiology;
Diagnosis;
Treatment
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(6):578-581
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze the epidemiological and clinical characteristics of novel coronavirus pneumonia (COVID-19), and to provide evidence for its further prevention and control.Methods:The epidemiological history, clinical symptoms, pulmonary CT changes, treatment plan (hormone intervention or not), and negative conversion time of nucleic acid were summarized and analyzed in 43 COVID-19 patients.Results:All the 43 patients had clear contact history, among which the number of patients transmitted from conference microphone was the largest (13 cases). There were 2 cases of critical disease, 4 cases of severe disease and 37 cases of common type. The main symptoms were fever (30 cases, 69.8%) and cough (40 cases, 72.1%). Lung CT mainly showed single or multiple ground glass shadows (40 cases), which were all absorbed by the treated lesions, among which 28 cases had a transient aggravation of the lesions during the treatment. All the 43 cases were treated with integrated traditional Chinese and western medicine, 2 cases in critical condition were treated with non-invasive ventilator, and 19 cases were treated with low-dose hormone. The average nucleic acid negative conversion time was 13.28 days, and the use of hormones had no significant effect on the negative conversion time ( P>0.05). Conclusions:COVID-19 of common type is the commonest. Early respiratory support therapy is recommended for critical cases. Hormone intervention makes no obvious influence on the negative conversion time of nucleic acid. Close contact in a closed environment greatly increases the risk of transmission.
