Progress in pathogenic spectrum and molecular epidemiology of hand, foot and mouth disease in China in the last decade

VernacularTitle:我国近十年手足口病病原谱及分子流行病学研究进展
Author: Meng ZHANG ¹ ; Xiangpeng CHEN ; Zhengde XIE
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1. 国家儿童医学中心　首都医科大学附属北京儿童医院　北京市儿科研究所感染与病毒研究室　中国医学科学院儿童危重感染诊治创新单元　国家呼吸系统疾病临床医学研究中心　儿科重大疾病研究教育部重点实验室　儿童呼吸道感染性疾病研究北京重点实验室，北京　100045
Keywords: Hand, foot, and mouth disease; Pathogenic spectrum; Molecular epidemiology
From: Chinese Journal of Experimental and Clinical Virology 2020;34(6):660-664
CountryChina
Language:Chinese
Abstract: Hand, foot, and mouth disease (HFMD) is an acute infectious disease caused by enteroviruses existing worldwide. Enterovirus 71 (EV-A71), Coxsackievirus A16 (CV-A16) and Coxsackievirus A6 (CV-A6) are the major pathogens of HFMD in the mainland of China. The pathogenic spectrum of HFMD has changed significantly in China. It is related to the epidemic pattern of enterovirus and may also be affected by the application of EV-A71 vaccine. This review focuses mainly on the epidemic patterns, the pathogenic spectrum and the molecular epidemiology of HFMD in the mainland of China.