Three cases of pure red cell aplasia caused by parvovirus B19 infection after solid organ transplantation and literature review
10.3760/cma.j.cn112866-20191230-00210
- VernacularTitle:实体器官移植后细小病毒B19感染导致单纯红细胞再生障碍性贫血3例并文献复习
- Author:
Huan ZHANG
1
;
Xia XIAO
;
Yuming LI
;
Mingfeng ZHAO
Author Information
1. 天津市第一中心医院 300192
- Keywords:
Solid organ transplantation;
Pure red cell aplasia;
Parvovirus
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(5):543-546
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Retrospective analysis of the occurrence, development, treatment and outcome of three cases of pure red cell aplasia(PRCA) caused by parvovirus B19 after solid organ transplantation and literature review.Methods:Three patients were diagnosed by typical clinical manifestations, laboratory tests, and bone marrow aspiration. The parvovirus DNA was found to be positive in all 3 patients, and case 3 was found to be co-infected with herpes zoster virus. The treatment included a combination of immunosuppressive agents, intravenous gamma globulin, antiviral, hematopoietic, and hematopoietic materials supplementation.Results:The patient′s anemia was corrected, and the viral DNA became negative. No recurrence was found during follow-up.Conclusions:The etiological diagnosis of PRCA after solid organ transplantation is crucial, and comprehensive treatment can have a good effect.
