Study on the therapeutic effect of drug ion implantation in patients with viral keratitis and bacterial keratitis
10.3760/cma.j.cn112866-20200506-00155
- VernacularTitle:药物离子导入技术在病毒性和细菌性角膜炎患者治疗中的应用
- Author:
Lanfang LU
1
;
Jianwei ZHAI
;
Wei SU
;
Shuang MIAO
;
Shuyan HE
Author Information
1. 广西河池市人民医院眼科 547000
- Keywords:
Drug ion implantation technique;
Viral keratitis;
Bacterial keratitis;
complications
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(5):532-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the therapeutic effect of drug ion implantation on viral or bacterial keratitis.Methods:A total of 200 patients with viral keratitis and another 200 patients with bacterial keratitis who were admitted to our hospital for ophthalmic treatment from April 2018 to April 2019 were selected as research subjects, through double-blind, prospective, randomized controlled method patients were divided into two groups, namely the control group given routine treatment, and drug treatment group cases were treated on the basis of the routine treatment with drug iontophoresis technology. The effective rate, visual acuity, length of stay, complication rate, half-year recurrence rate and nursing satisfaction were observed.Results:The treatment effective rate of the experimental group was 100%, the effective rate of vision treatment was 100%, and the nursing satisfaction rate was 93%, which was significantly higher than that of the control group, ( χ2=4.082, P=0.043; χ2=4.082, P=0.043; χ2=59.282, P<0.001). The duration of hospitalization of the patients in the experimental group (8.93±1.69)d, the cost of hospitalization (5627.12±482.34) yuan, the recurrence rate of half a year was 2%, and the incidence of complications was 4%, which was significantly lower than that of the control group ( t=6.522, P=0.000; t=10.985, P<0.001; χ2=5.674, P=0.017; χ2=10.010, P=0.002). Conclusions:Drug ion implantation technology wasbetter than conventional drug treatment in the treatment of viral and bacterial keratitis, and the treatment operation is more convenient, did not produce adverse reactions, is worth promoting in ophthalmic treatment as an optional treatment method .