Prevalence and genotypes of parechovirus A in hospitalized children with acute gastroenteritis in Fuzhou, China

VernacularTitle:福州市腹泻住院儿童中A组双埃可病毒流行情况及基因型别分析
Author: Zhimiao HUANG ¹ ; Bingshan WU ; Weidong LIN ; Yuwei WENG
Author Information

1. 福建省疾病预防控制中心　福建省人兽共患病研究重点实验室，福州　350001
Keywords: Parechovirus A; Genotype; Hospitalized children; Diarrhea
From: Chinese Journal of Experimental and Clinical Virology 2020;34(3):289-292
CountryChina
Language:Chinese
Abstract: Objective:To investigate the prevalence and genotypes of parechovirus A (PeV-A) in hospitalized children with acute gastroenteritis under 5 years of age in Fuzhou, China.Methods:We performed a real-time RT-PCR to screen for PeV-A from stool samples and amplify VP3/VP1 junction region by nested RT-PCR to identify PeV-A type.Results:The result showed that 28 of 316 (8.86%) children with acute gastroenteritis were positive for PeV-A, two cases were co-infected with calicivirus, none with rotavirus, adenovirus or astrovirus. Totally 21 cases were PeV-A1, 1 case was PeV-A3 and 2 cases were PeV-A6 among 24 cases who were positive for PeV-A; PeV-A1 was the most prevalent strain with the proportion of 87.5%. The infection with PeV-A mainly occurred in children under 1 year of age and was prevalent between August and October.Conclusions:PeV-A1 was a main pathogen in PeV-A in hospitalized children with acute gastroenteritis in Fuzhou, and the children under 1 year of age were the main target population of PeV-A1.