Analysis on the surveillance results of influenza virus in Gansu province, 2010-2018
10.3760/cma.j.cn112866-20190919-00146
- VernacularTitle:甘肃省2010—2018年度流感病毒监测结果分析
- Author:
Hui ZHANG
1
;
Hongyu LI
;
Congshan XU
;
Baodi LI
;
Zhongyi JIANG
;
Deshan YU
;
Zimei LIU
;
Jian HE
Author Information
1. 甘肃省疾病预防控制中心，兰州 730000
- Keywords:
Influenza-like illness;
Influenza virus;
Surveillance;
Nucleic acid detection;
Virus isolation
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(3):276-279
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the influenza surveillance results and epidemiological characteristics of the disease in Gansu province in 2010-2018, and provide scientific basis for the formulation and adjustment of influenza prevention and control strategies.Methods:Real-time PCR was used to detect the specimens of ILI illness (ILI) cases reported by 19 national influenza surveillance sentinel hospitals in Gansu province. Influenza virus isolation and culture were carried out using canine kidney cells (MDCK).Results:Total of 93 334 specimens from ILI cases were collected from Jan. 2010 to Dec. 2018, and 13 439 samples were positive for influenza virus nucleic acid. The positive rate of viral nucleic acid detection was 14.40%, and the proportion of influenza B virus in positive samples was the highest (37.02%), and seasonal H3N2 influenza virus (35.25%), H1N1 influenza virus (26.78%). The advantages are different in various periods. The peak period of influenza is from Dec. to Mar., and the highest incidence rate is in the age group of 5-15 years (20.34%). The incidence rates of the other age groups are similar. The difference of influenza positive rate in different age groups is statistically significant ( χ2=775.153, P<0.001), but in male and female was not significant. Total of 16 101 ILI specimens positive for influenza virus nucleic acid were subjected to virus isolation and cultured, and 3 892 strains of influenza virus were isolated, of which influenza B virus accounted for the highest proportion (37.82%), followed by seasonal H3N2 influenza virus (33.04%), H1N1 influenza virus (28.96%). Conclusions:The epidemic of influenza in Gansu province had an obvious regularity, and it was undulating and prevalent. It is necessary to strengthen prevention and control measures among school-age children and adolescents.
