Progress in anti-viral treatment of rabies
10.3760/cma.j.cn112866-20190506-0063
- VernacularTitle:狂犬病抗病毒治疗研究进展
- Author:
Xiankun WANG
1
;
Meihua SONG
;
Zhihai CHEN
Author Information
1. 首都医科大学附属北京地坛医院,北京 100015
- Keywords:
Rabies;
Anti-vital treatments;
Progress in researches
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(2):221-224
- CountryChina
- Language:Chinese
-
Abstract:
Rabies is a fatal zoonotic disease caused by rabies virus (RABV). The rabies vaccine, immunoglobulin, and Milwaukee therapy that have emerged have not reached the cure for rabies, and antiviral treatment against the virus itself has become a concern and focus. In this review article, according to the RABV replication infection process, the mechanism of action of antiviral drugs acting on various processes of the virus, relevant experimental procedures and result are briefly described, and the evaluation of the efficacy of new anti-RABV drugs and the direction of the combination therapy are proposed.