Analysis of etiology of severe acute respiratory infection cases in Kunming from 2018 to 2019
10.3760/cma.j.cn112866-20191224-00205
- VernacularTitle:2018—2019年昆明地区严重急性呼吸道感染病例病原学分析
- Author:
Jienan ZHOU
1
;
Xiaonan ZHAO
;
Yanhong SUN
;
Yaoyao CHEN
Author Information
1. 云南省疾病预防控制中心，昆明 650022
- Keywords:
Severe acute respiratory infection;
Hospitalized cases;
Respiratory pathogen;
Surveillance
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(2):165-168
- CountryChina
- Language:Chinese
-
Abstract:
Objective:By analyzing the viral pathogen spectrum and epidemiological characteristics of hospitalized severe acute respiratory infection (SARI) cases in Kunming city to provide the pathogenic basis for the clinical diagnosis, treatment, prevention and control of acute respiratory tract infection.Methods:Respiratory viruses were detected by real-time PCR, and the results were statistically analyzed using software SPSS20.0.Results:A total of 291 SARI cases’ pharyngeal swab specimens were detected from January 2018 to March 2019, and 86 positive specimens were detected, the positive rate was 29.55%. The top three pathogens detected were human influenza A virus (11.34%), human metapneumovirus (3.44%), and human respiratory syncytial virus (3.09%), and there were 6 specimens with mixed infection of two viruses, and the mixed infection rate was 2.06%. The virus detection rate of male cases was higher than that of female cases ( χ2=6.183, P=0.013), and the positive rate of virus detection was the highest in the 2 to 5 years age group, and positive respiratory virus detection peaks were in the fourth and the first quarter. Comparison of virus positive and negative group showed that there were no statistically significant differences in clinical symptoms, signs, complications and underlying diseases between the two groups except for expectorant cough ( χ2=5.107, P=0.024) and runny nose ( χ2=4.683, P=0.030). Conclusions:Influenza virus is the main pathogen of SARI cases in Kunming city, and the detected pathogens have certain epidemic rules in different age groups and seasons.
