Clinical discussion on the application of invigorating spleen and benefiting qi and controlling blood method for the treatment of cancer therapy-related thrombopenia
10.3969/j.issn.1006-2157.2024.06.011
- VernacularTitle:应用健脾益气摄血法论治肿瘤治疗相关性血小板减少症的临证探讨
- Author:
Xiang YAN
1
;
Mei LUO
;
Jiahui YU
;
Yayue ZHANG
;
Shaodan TIAN
;
Xinyi CHEN
;
Menghao LAN
Author Information
1. 北京中医药大学东直门医院血液肿瘤科 北京 100700
- Keywords:
cancer therapy-related thrombopenia;
medicinal poison purpura;
invigorating spleen and ben-efiting qi and controlling blood method;
spleen controlling blood
- From:
Journal of Beijing University of Traditional Chinese Medicine
2024;47(6):808-812
- CountryChina
- Language:Chinese
-
Abstract:
Cancer therapy-related thrombopenia,which is called"medicinal poison purpura"in tradi-tional Chinese medicine,is a common hematologic adverse reaction during oncology treatment that is dif-ficult to treat due to the differences in oncology treatments and the complexity of the pathogenesis,resul-ting in various degrees of thrombocytopenia.Based on the theory that"spleen controlling blood",this pa-per believes that"medicinal poison purpura"is mainly caused by direct damage to the blood and qi by medicinal poison,leading to qi and blood deficiency;it also attacks the spleen and stomach,resulting in the deficiency of spleen qi and no source of qi and blood production.Due to the spleen deficiency,there is no essence to nourish kidney and bone marrow;their function of generating blood decreases,eventually it becomes"medicinal poison purpura".The theory of"regulating balance and flat regulation"is an im-portant academic idea of our team in the treatment of malignant hematological tumors.In this paper,we have systematically elaborated on the etiology,pathogenesis,and therapeutic principles of the treatment of cancer therapy-related thrombopenia with spleen deficiency pattern through the collation of relevant lit-erature.We believe that the prescription formulated according to the method of invigorating spleen and benefiting qi and controlling blood for the treatment of cancer therapy-associated thrombocytopenia with spleen deficiency pattern is in line with the principle of correspondence between prescription and syn-drome,and correspondence between drugs and syndrome in traditional Chinese medicine,which is theo-retically feasible and has a high clinical application value.
