Levels of antibody to measles, rubella and mumps viruses in a healthy population in Sichuan province in 2018
10.3760/cma.j.issn.1003-9279.2020.01.006
- VernacularTitle:四川省2018年健康人群麻疹、风疹、流行性腮腺炎抗体水平监测
- Author:
Chaohua XU
1
;
Jilan HE
;
Wenbin TONG
;
Li LIU
Author Information
1. 四川省疾病预防控制中心微生物检验所
- Keywords:
Measles;
Rubella;
Mumps;
Antibody levels
- From:
Chinese Journal of Experimental and Clinical Virology
2020;34(1):29-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of antibody to measles,rubella and mumps viruses in healthy population in Sichuan province,2018.Methods Totally 1 901 healthy people were selected from 7 age groups in 9 counties of Sichuan province.Serum samples of them were collected to test the IgG antibody to measles,rubella and mumps viruses by enzyme-linked immunosorbent assay (ELISA),and analyzed statistically.Results In 1 901 subjects,the positivity rates of measles,rubella and mumps IgG antibody were 83.69％,71.59％,63.12％ respectively,and the geometric mean titer (GMCs) were 1 289.92 mIU/ ml,87.63 IU/ml,and 425.62 U/ml respectively.There were significant differences in positivity rates of measles,rubella and mumps antibody among age groups and counties.There were no significant differences in GMCs of measles antibody among age groups and among counties,and the samples with full protection of measles (GMC≥ 1 000 mIU/ml) accounted for only 34.19％.There were significant differences in GMCs of rubella and mumps antibody among age groups and among counties.Conclusions The levels of antibody to measles,rubella and mumps were lower in healthy population in Sichuan.Vaccination should be strengthened in vulnerable areas and age groups.
