A Case of Castleman's Disease with Kidney Involvement.
- Author:
Ji Eon WON
1
;
Seon Ju JEONG
;
Jai Hyeun CHO
;
Je Yeol KIM
;
Eun Jeong KIM
;
Hyeong Jik KIM
;
Young Rim SONG
;
Eun Sook NAM
;
Seong Gyun KIM
Author Information
1. Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea. sgkim@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Castleman's disease;
Plasma cells;
Kidney
- MeSH:
Azotemia;
Biopsy;
Giant Lymph Node Hyperplasia*;
Humans;
Hyalin;
Kidney*;
Lymph Nodes;
Lymphatic Diseases;
Lymphoid Tissue;
Male;
Middle Aged;
Needles;
Plasma Cells;
Proteinuria;
Weight Loss
- From:Korean Journal of Nephrology
2007;26(6):767-771
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Castleman's disease is a rare disorder of unknown etiology that results in the unregulated growth of lymphoid tissue. It can be classified as unicentric and multicentric based on clinical and radiological findings, and also as hyaline vascular and plasma cell type based on histopathology. Castleman's disease may present as an asymptomatic involvement of one lymph node group or as a multicentric disease with systemic features. However, renal involvement is very rare. Here we report a 50-year old male patient with histopathologically proven multicentric plasma cell type of Castleman's disease who presented with weight loss, palpable cervical lymphadenopathy, azotemia and proteinuria. The finding of a percutaneous needle renal biopsy was compatible with plasma cell type of Castleman's disease. After treated with systemic corticosteroid, azotemia and proteinuria disappeared.
