Distribution characteristics of human papillomavirus type 39 in Beijing

VernacularTitle:北京地区人乳头瘤病毒39型的人群分布特征
Author: Peili JI ¹ ; Fenfen JIANG ; Ying LI ; Hongtu LIU
Author Information

1. 中国疾病预防控制中心病毒病预防控制所病毒相关肿瘤室
Keywords: Papillomavirus,Human; Prevalence; Gene
From: Chinese Journal of Experimental and Clinical Virology 2016;30(4):365-368
CountryChina
Language:Chinese
Abstract: Objective To investigate the infection rate and distribution of human papillomavirus type 39 in Beijing.Methods HPV genotyping detection coupled with cytological test of cervical exfoliated cells within 30 days were used for the patients from the People's Liberation Army General Hospital,between January 2013 to July 2014.Full-length genomes were amplified for the HPV39 positive samples.Results Among 19 018 samples,518 were HPV39 positive (2.72％).Two peaks were observed in the age groups 21-25 and 46-50 years old,with positive rate of 2.98％ and 2.44％ respectively.The prevalence of HPV39 in low-grade squamous intraepithelial lesion (LSIL) was 18.52％,higher than other cervical lesion groups.In addition,full-length genome amplifications were successful in five HPV39 positive samples.Conclusions In the studied population,HPV39 showed two increases in age groups,and abundance in LSIL.Episomal form of HPV39 viral genomes existed in the samples.