Molecular diagnostic analysis of hepatitis patients with HDV IgM antibody positive and the HBV surface Antigen-negative
10.3760/cma.j.issn.1003-9279.2016.03.012
- VernacularTitle:1例HDV抗体IgM阳性HBV S抗原阴性的肝炎患者分子诊断分析
- Author:
Xuexin LU
1
;
Yao YI
;
Qiudong SU
;
Shengli BI
Author Information
1. 中国疾病预防控制中心病毒病预防控制所
- Keywords:
HDV;
co-infection;
antibody for HDV;
Nucleic Diagnostics
- From:
Chinese Journal of Experimental and Clinical Virology
2016;30(3):303-306
- CountryChina
- Language:Chinese
-
Abstract:
Objective In order to further accurate diagnosis of the special serum with HDV IgM antibody positive but conventional HBV five detection negative.Methods designing the specific primers,by extracting the nucleic acid of the virus in the serum,amplifying the virus genome conservative region,and then blast the sequences in Genebak.Results In this study,the HDV and HBV conserved regions were amplified in the serum,after blast,the amplified sequences were found to be consistent with the conserved regions of HBV and HDV.Conclusion In clinical,HDV infection will appears in the serum of HDV antibody IgM positive but HBV S antigen negative,it should cause more attention in clinic for HDV infected.
