Pathogenesis of diabetic nephropathy with essence depletion and collateral impediment
10.3969/j.issn.1006-2157.2019.01.002
- VernacularTitle:糖尿病肾病"精损络痹"病机探讨
- Author:
Jiyuan HU
1
;
Hongfang LIU
;
Xiangwei ZHANG
Author Information
1. 安徽中医药大学
- Keywords:
diabetic nephropathy;
core pathogenesis;
essence depletion;
collateral impediment;
kidney essence
- From:
Journal of Beijing University of Traditional Chinese Medicine
2019;42(1):8-11
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of essence depletion and collateral impediment can summarize the characteristics of core pathogenesis of diabetic nephropathy (DN) and guide clinical treatment effectively.The pathogenesis of essence depletion emphasizes that kidney lesions is the core of five viscera lesions.Kidney deficiency indicates the consumption of kidney essence and deficiency induces the production of stagnation, dampness, stasis and turbidity.The pathogenesis of collateral impediment indicates that dampness, stasis and turbidity due to deficiency obstruct kidney collateral, even aggregation-accumulation is produced.Therefore collateral impediment is characterized by excess due to deficiency.The therapy of filling essence and freeing collaterals is proposed for DN treatment in the paper.The filling essence refers to nourishing kidney essence, and freeing collaterals refers to eliminating pathogens to free collaterals.It is a kernel therapy for DN.The nourishing kidney essence is a cornerstone in DN treatment, especially in middle or late stages of DN treatment.In early stage eliminating pathogens to resolve impediment (eliminating-freeing therapy) is stressed, and in late stage reinforcing healthy qi and eliminating pathogens (nourishing-freeing therapy) is emphasized.The healthy qi will not be damaged during eliminating pathogens.
