Influence of Chinese medicinals with functions of activating blood and re-moving toxicity on inflammatory markers and blood fat in patients with acute coronary syndrome after percutaneous coronary intervention
10.3969/j.issn.1006-2157.2018.05.012
- VernacularTitle:活血解毒中药对急性冠脉综合征患者介入术后炎症标记物和血脂的影响
- Author:
Ming GUO
1
;
Zhuye GAO
;
Peili WANG
;
Dazhuo SHI
Author Information
1. 中国中医科学院西苑医院 北京100091
- Keywords:
activating blood and removing toxicity;
coronary heart disease;
inflammatory markers;
blood fat
- From:
Journal of Beijing University of Traditional Chinese Medicine
2018;41(5):423-427
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of routine statins drugs combined with Guanxin Danshen (Coronary Salvia Root)Gutta Pills and Chuanxinlian(Andrographitis)Tablet on serum inflammatory markers and blood fat in patients with acute coronary syndrome(ACS)after percutaneous coronary inter-vention(PCI).Methods ACS patient(n=40)were randomly divided into control group and treatment group(each n=20)after PCI.The control group was treated with basic therapy of Western medicine and statins,and treatment group was additionally given Guanxin Danshen Gutta Pills and Chuanxinlian Tablet for 30 d.The levels of serum high sensitivity C-reactive protein(hs-CRP), tumor necrosis factor-α (TNF-α)and blood fat were detected by using ELISA,and integrals of blood stasis pattern were calculat-ed.Results The levels of hs-CRP and TNF-αdecreased significantly in 2 groups after treatment(P<0.05 or P<0.01), and difference between 2 groups had statistical significance after treatment(P<0.01).The level of serum total cholesterol(TC)decreased significantly and level of high-density lipo-protein-cholesterol(HDL-C increased in treatment group(P<0.05).The integrals of blood stasis pat-tern decreased significantly in treatment group after treatment(P<0.01).Conclusion Guanxin Dan-shen Gutta Pills and Chuanxinlian Tablet,with effects of activating blood and removing toxicity,can fur-ther reduce the levels of inflammatory markers, hs-CRP and TNF-α, relieve blood stasis and assist to control blood fat in patients with ACS after PCI.
