Risk factors for bacterial infection of 24 H7N9 inpatients in Shenzhen

VernacularTitle:深圳24例H7N9患者合并细菌感染危险因素分析
Author: Xi LIU ¹ ; Jing YUAN ; Zheng YANG ; Wenfei WANG ; Xinchun CHEN ; Boping ZHOU
Author Information

1. 中山大学附属第五医院感染科
Keywords: H7N9; Bacterial infection; Risk factor
From: Chinese Journal of Experimental and Clinical Virology 2016;30(2):179-181
CountryChina
Language:Chinese
Abstract: Objective To investigate the risk factors for bacterial infection of H7N9 inpatients,and provide reference for the prevention of bacterial infection.Methods The clinical and bacterial infection data in 24 H7N9 infections in Shenzhen from Dec 2013 to May 2014 was retrospectively analyzed.Results A total of 10 cases were infected with an infection rate of 41.7％.The lung was the main infected sites.Of all the bacteria isolated,there were 20 strains of gram-negative bacillus (64.5％),11 strains of grampositive cocci (35.5％).7 patients encountered extensively drug resistant acinetobacter baumannii.The risks factors for bacterial infection of H7N9 inpatients were delayed antiviral therapy,invasive mechanical ventilation,severe ARDS,lower lever of lymphocytes,CD4 + cells and oxygenation indexes,persistent lymphocytopenia.Conclusions The incidence of bacterial infection in H7N9 patients is relatively high;there are so many risk factors that we should take corresponding measures to effectively reduce the incidence.