The relationship between PrP protein expression and the clinical degrees and the pathological grade of head and neck squamous cell carcinomas
10.3760/cma.j.issn.1003-9279.2016.02.003
- VernacularTitle:PrP蛋白的表达与头颈部鳞状细胞癌患者临床进展及病理分级的关系
- Author:
Wei WEI
1
;
Juntao JIN
;
Baoyun ZHANG
;
Yuntao SONG
;
Naisong ZHANG
;
Xiaoping DONG
;
Qi SHI
Author Information
1. 北京大学肿瘤医院暨北京市肿瘤防治研究所头颈外科恶性肿瘤发病机制及转化研究教育部重点实验室
- Keywords:
Head and neck cancer;
Neoplasms,squamous cell;
PrP Protein
- From:
Chinese Journal of Experimental and Clinical Virology
2016;30(2):120-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the PrP protein expression and the clinical degrees and pathological grade of head and neck squamous cell carcinomas.Methods Immunohistochemistry technique was used to test the PrP protein expression in the 92 head and neck squamous cell carcinomas cases.SPSS software was used to analyze the relationship between the PrP protein and the clinical degrees and pathological grade of head and neck squamous cell carcinomas.Results In the 92 head and neck squamous cell carcinomas cases,the positive rate of PrP protein was different with the sites of the carcinomas,the clinical degree and the pathological grade.Conclusion High expression of PrP protein related with the occurrence and development of head and neck squamous cell carcinomas.
