research of cornea superficial temperature in herpes simplex keratitis and its relationship with cornea lesion
10.3760/cma.j.issn.1003-9279.2016.01.005
- VernacularTitle:单纯疱疹病毒性角膜炎兔角膜表面温度的改变与角膜损伤关系的研究
- Author:
Ying YU
1
;
Wanhong MIAO
;
Fang ZHAO
;
Feifei LI
Author Information
1. 201203,上海中医药大学附属曙光医院
- Keywords:
Herpes simplex keratitis;
Cornea temperature;
Cornea lesion;
Experiment research
- From:
Chinese Journal of Experimental and Clinical Virology
2016;(1):19-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of cornea superficial temperature of herpes simplex keratitis( HSK) rabbits and the relationship between corneal temperature with cornea lesion.Methods The right eyes of the 12 rabbits that were diagnosed as HSK by being inoculated HSV-1KOS virus to the cornea were brought into the experiment group.The 12 right eyes of the control group were dealt with incision on the cornea epithelial layer without virus.The corneal temperature was measured with the infrared thermometer. The scale of epithelia damage, lesion of stroma and neovascular were observed before and at the 1st day, 3rd day, 7th day, 14th day after establishment of the HSK model.Results The cornea superficial temperature of herpes simplex keratitis was 31.14 ±1.12℃.The temperatures at the 3rd day, 7th day, 14th day were all higher than those of the control group (P<0.01, P<0.05).The stroma opacity were rather serious at the 3rd day, 7th day, 14th day, and the temperatures of the 3rd day and 7th day were relevant to the degrees of stroma opacity(P<0.05).The neovascular was significantly increased at the 14th day, which was relevant to the cornea temperature ( P<0.05) .Conclusion The cornea superficial temperature was increased in the case of herpes simplex keratitis, and the temperature was relevant to the degree of stroma opacity and neovascular.
