Lymphocytic Hypophysitis: A Cases Report.
- Author:
Dong Jun LIM
1
;
Yong Gu CHUNG
;
Hoon Kap LEE
;
Ki Chan LEE
;
Jung Keun SUH
Author Information
1. Department of Neurosurgery, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Lymphocytic hypophysitis;
Pituitary tumor;
SLE;
Systemic lupus erythematosus
- MeSH:
Autoimmune Diseases;
Diagnosis;
Female;
Headache;
Hemorrhage;
Humans;
Hypopituitarism;
Lupus Erythematosus, Systemic;
Magnetic Resonance Imaging;
Pituitary Gland;
Pituitary Neoplasms;
Young Adult
- From:Journal of Korean Neurosurgical Society
1998;27(11):1611-1614
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland that is being recognized increasingly as a cause of hypopituitarism. Lymphocytic hypophysitis is due to autoimmune pituitary destruction and often occurs with other autoimmune diseases. We report a rare case of lymphocytic hyphophisitis in a 21-year old woman, who suffered from systemic lupus erythematosus(SLE), presenting with intermittent headache for 2 months. Magnetic Resonance Imaging with a contrast medium revealed expanding sellar mass with hemorrhage. The patient underwent transsphenoidal surgery with a provisional diagnosis of pituitary adenoma. Histological examination revealed evidence of lymphocytic hypophysitis. We report a case of lymphocytic hypophysitis in nonpregnant women who suffered from SLE, an immunologically mediated multisystem disease.