The expression and clinical significance of viral macrophage inflammatory protein vMIP-Ⅰ and vMIP-Ⅱ in Kapsi's sarcoma patients
10.3760/cma.j.issn.1003-9279.2015.05.009
- VernacularTitle:病毒巨噬细胞炎症蛋白vMIP-Ⅰ和vMIP-Ⅱ在Kaposi's肉瘤患者中的表达及意义
- Author:
Xiaodong WANG
1
;
Han JIANG
;
Ping HOU
;
Dalihan · DUOLAND
;
Haojia LUO
;
Ping MA
;
Ablize · PALIHAN
Author Information
1. 新疆医科大学第一附属医院
- Keywords:
Virus macrophage inflammatory protein;
Kaposi's sarcoma;
Kaposi's sarcoma-associated herpesvirus;
Sarcoma
- From:
Chinese Journal of Experimental and Clinical Virology
2015;29(5):421-424
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression in sarcoma tissue,blood,salivaand urine of KSHV-encoded virus macrophage inflammatory protein vMIP-Ⅰ,vMIP-Ⅱ.Methods Genomic DNA was extracted from samples in 8 classic Kapsi' s sarcoma patients of Xinjiang,vMIP-Ⅰ and vMIP-Ⅱ gene were amplified by PCR.Results Genomic DNA were detected from sarcoma tissue,blood,saliva and urine of 8 classic Kapsi' s sarcoma patients,while vMIP-Ⅰ and vMIP-Ⅱ were amplified from all tissue samples,but the expression of vMIP-Ⅰ and vMIP-Ⅱ in blood,saliva and urine was negtive.Conclusions There is special expression of vMIP-Ⅰ and vMIP-Ⅱ in Kapsi' s sarcoma tissue.It provides a preliminary basis for further study of the mechanism of angiogenesis Kaposi's sarcoma.
