Quality analysis on fresh Danshen (Radix Salviae Miltiorrhizae, Red Sage Root) from different producing areas based on technology of high-resolution liquid chromatography-mass spectrometry
10.3969/j.issn.1006-2157.2017.11.013
- VernacularTitle:基于高分辨液质联用技术的不同产地鲜丹参药材品质分析
- Author:
Yuanyang SHAO
1
;
Guojie XU
;
Xiaoyan JIN
;
Siqi LIU
;
Chi ZHANG
;
Juan WANG
;
Shuangshuang MA
;
Caijuan ZHANG
;
Minyi QIU
;
Chunsheng LIU
;
Xueyong WANG
Author Information
1. 北京中医药大学中药学院 北京100102
- Keywords:
Danshen (Radix Salviae Miltiorrhizae,Red Sage Root);
content determination;
principal component analysis;
partial least square analysis;
variation
- From:
Journal of Beijing University of Traditional Chinese Medicine
2017;40(11):946-953
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the content of active components in fresh Danshen Radix Salviae Miltiorrhizae,Red Sage Root) from different producing areas,and review reasonably the medicinal quality of fresh Danshen.Methods The content of 5 salvianolic acids and 12 tanshinones in fresh Danshen,from 7 different producing areas,were determined by applying LTQ-Orbitrap XL high-resolution mass spectrometer.On this basis,all content were analyzed by using principal component analysis (PCA) and partial least square (PLS) analysis.Results The content of active components in fresh Danshen from the same producing area were basically the same,and difference was significant in content of active components among fresh Danshen from different producing areas.The content of salvianolic acids was the highest in fresh Danshen from Hubei,and content of tanshinone Ⅰ and tanshinone ⅡA were the highest in fresh Danshen from Sichuan and Henan.The analysis results of PCA and PLS showed that the distribution of most active components had a distinct regional specificity.Conclusion The difference is significant in quality of fresh Danshen from different producing areas,and they have a distinct regional specificity.Using fresh Danshen as quality evaluation materials,that is a useful supplement to review quality of raw medicinal materials based on dry herbs.It explored a new and more comprehensive approach for reviewing other Chinese medicinal materials.
