Early and late clinical outcomes after primary stenting of the unprotected left main coronary artery stenosis in the setting of acute myocardial infarction.
- Author:
Myung Zoon YI
1
;
Seung Whan LEE
;
Sae Hwan LEE
;
Chang Bum PARK
;
Sung Du KIM
;
Song Yi HAN
;
Young Hak KIM
;
Cheol Whan LEE
;
Myeong Ki HONG
;
Jae Joong KIM
;
Seong Wook PARK
;
Seung Jung PARK
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. sjpark@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Stent;
Acute myocardial infarction;
Coronary arteriosclerosis
- MeSH:
Constriction, Pathologic;
Coronary Artery Disease;
Coronary Disease;
Coronary Stenosis*;
Coronary Vessels*;
Follow-Up Studies;
Freedom;
Hemodynamics;
Humans;
Mortality;
Myocardial Infarction*;
Shock, Cardiogenic;
Stents*
- From:Korean Journal of Medicine
2004;67(3):249-254
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Acute left main coronary artery occlusion is a dramatic condition with very high mortality. The study was aimed to evaluate the effect of primary stenting in patients with left main coronary artery disease in the setting of acute myocardial infarction. METHODS: Between June 1997 and April 2002, primary stenting for left main coronary artery disease was performed in eighteen patients with acute myocardial infarction. We evaluated clinical outcomes and prognostic determinants in this clinical setting. RESULTS: Mean ages of patients were 59 +/- 12 years. Fourteen patients had cardiogenic shock on admission. Angiographic success (TIMI flow >or= 2 and diameter stenosis < 30% after stenting) was achieved in 17 patients (94%). In-hospital death occurred in 8 patients (44%). Two patients (11%) received emergent bypass surgery because of hemodynamic instability after primary stenting. On univariate analysis, good pre-intervention TIMI flow (grade >or= 2) was identified as a good prognostic determinant of in-hospital survival. During mean follow-up of 39 +/- 22 months, there was no late death and 1 patient received bypass surgery. Probability of freedom from death at 3-year was 56 +/- 12%. CONCLUSION: Primary stenting is a valuable therapeutic strategy for left main coronary disease in the setting of acute myocardial infarction, and it might save the life especially in patients with good pre-intervention TIMI flow (grade >or= 2). Long-term clinical outcome of patients surviving to hospital discharge is favorable.
