Studies of the effects on serum VEGF level in patients with glioma
10.3760/cma.j.issn.1003-9279.2015.01.019
- VernacularTitle:脑胶质瘤对患者血清VEGF表达水平的影响
- Author:
Zhengquan ZHU
1
;
Dushanbieke.Kezi
;
Haicheng XIA
;
Liang LIU
;
Changjiu TANG
;
Damin ZHANG
Author Information
1. 830011,新疆医科大学附属肿瘤医院神经外科
- Keywords:
Glioma;
Endothelium,vascular;
Growth substances
- From:
Chinese Journal of Experimental and Clinical Virology
2015;29(1):56-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of the serum vascular endothelial growth factor (VEGF) in the glioma patients by the malignant degress.Methods Quantitative analysis the serum VEGF levels with the double antibody sandwich assay (ELISA) for 35 cases of glioma patients and 10 cases of healthy human and analyze the correlation of them.Results Mean serum VEGF expression in glioma patients was 120.71 ±45.99 pg/ml,normal value of the healthy people was 63.70 ± 6.50,the difference was statistically significant (P ＜0.05); serum VEGF expression was 156.43 ± 14.90 pg/ml in high-grade glioma patients (Ⅲ-Ⅳ grade) and 67.14 ± 6.12 pg/ml in low-grade glioma patients (Ⅰ-Ⅱ grade),the difference was statistically significant (P ＜ 0.05) ; there' s no different from low-grade glioma patients (Ⅰ-Ⅱ grade) and nomal(P ＞ 0.05).Conclusion The serum VEGF levels in the glioma patients was influence by the malignant degress.
