Clinical effect of traditional Chinese medicine therapy on perimenopausal insomnia from the standpoint of regulating liver and kidney:a Meta-analysis
10.3969/j.issn.1006-2157.2017.02.016
- VernacularTitle:从肝肾论治围绝经期失眠的临床疗效Meta分析
- Author:
Yidong GAO
1
;
Songtao ZHANG
;
Junshan HUANG
;
Likun XIE
;
Xiafei ZHAN
;
Jingjing DENG
Author Information
1. 福建中医药大学 福建 350000
- Keywords:
perimenopause;
insomnia;
therapy on perimenopausal insomnia from the standpoint of regulating liver and kidney;
Meta-analysis;
systematic review
- From:
Journal of Beijing University of Traditional Chinese Medicine
2017;40(2):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the clinical efficacy and safety of the traditional Chinese medicine(TCM) therapy on perimenopausal insomnia from the standpoint of regulating liver and kidney.Methods Randomized controlled trials(RCT) on PubMed, EMbase, CNKI, Wanfang Database and VIP database from their inception to April 2016 were searched.Two researchers separately screened the literature, extracted data and evaluated the literature bias risk according to inclusive criteria and exclusive criteria.Then the Meta-analysis was operated using Rev Man 5.3 software.Results Altogether nine RCT with 678 patients were eligible.The result of Meta-analysis showed: the clinical effectiveness of experimental group (TCM therapy group) was superior to that of control group(RR=1.30,95%CI[1.11,1.52],P<0.05);the PSQI scores showed significant differences between the two groups (SMD=-1.16,95%CI[-2.12,-0.20],P<0.05),but SPIEGEL score did not.Although adverse reactions were appeared in five studies, the adverse reaction rate of the experimental group was lower significantly (RR=0.09,95%CI[0.04,0.22],P<0.05).Conclusion The experimental group achieved obvious clinical efficacy with less adverse effect.
