Separation and identification of chemical constituents of Mongolian medi-cine compound Shudage-4
10.3969/j.issn.1006-2157.2016.11.010
- VernacularTitle:蒙药复方述达格-4化学成分的分离与结构鉴定
- Author:
Shasha XIN
1
;
Yinfei DU
;
Xin JIA
;
Yang YANG
;
Yu DONG
Author Information
1. 内蒙古医科大学药学院 内蒙古 010110
- Keywords:
Mongolia medicine compound Shudage-4;
chemical constituent;
structure identification
- From:
Journal of Beijing University of Traditional Chinese Medicine
2016;39(11):941-944
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Mongolian medicine compound Shudage-4, so as to find out material bases of its pharmacodynamic effects.Methods The chemical constitutes of Shudage-4 were extracted using ethanol extraction method,and were isolated and purified using technolo-gies of silica gel,Sephadex LH-20 and reversed phase silica gel.Then the structures of the isolated com-pounds were identified by using different spectroscopic and chromatographic techniques including ultra vi-olet spectroscopy(UV),infrared spectroscopy(IR),mass spectrometry(MS)and nuclear magnetic reso-nance(NMR).Results There were 10 compounds isolated and identified from Mongolian medicine Shudage-4—1-phenyl-7-(3-methoxy-4-hydroxy) phenyl-5-ol-3-heptanone-one (1 ),stigmasterol (2 ), kaempferol(3),daucosterol(4),p-Anisic acid(5),ursolic acid(6),oleanic acid (7),dehydrocostus lactone(8),costunolide(9)and dehydrodiisoeugenol (10).Conclusion The ten compounds,except stigmasterol,were first isolated from Shudage-4.This paper provided important scientific data for the ma-terial bases of Mongolian medicine Shudage-4.
