Detection and analysis of protein chip technology in 391 patients with respiratory airway infection
10.3760/cma.j.issn.1003-9279.2014.02.027
- VernacularTitle:391例呼吸道感染的病原学蛋白芯片技术检测与分析
- Author:
Liming NIU
1
;
Qunli DING
;
Xiaolei YE
;
Feng WEI
Author Information
1. 315020,宁波大学医学院附属医院呼吸内科
- Keywords:
Respiratory tract infections;
Respirovirus;
Pneumoniae mycoplasmal;
Chlamydia pneumoniae
- From:
Chinese Journal of Experimental and Clinical Virology
2014;28(2):150-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathogen in adult airway infection of Baise city.Method A total of 391 cases (both outpatient and inpatient)of airway infection were collected.Serum IgM titer of six pathogen(influenza virus,Ⅳ; respiratory syncytial virus,RSV; Coxsackievirus B,CVB; adenovirus,ADV ; mycoplasmal pneumoniae,MP;Chlamydia pneumoniae,CPN) were tested for two times at acute stage and convalescent period respectively.Protein chip technology was used to test the IgM antibody.Results 180 samples were positive,the total positive rate was 46.06％.the positive rate of MP was 18.33％,14.44％ for CPN.Among mixed infection,MP combined with ADV positive rate was 7.78％,5.00％ for MP combined with CPN.The positive rate for cases which MP IgM antibody was positive and had clinical symptoms at acute stage was 89.55％.The positive rate for cases which MP IgM antibody was positive at acute stage and rose 4 times at convalescent period was 86.57％.There was no significant difference between them (P ＞ O.05).We got the same result for The positive rate for CPN IgM antibody.Conclusion The positive rate for IgM antibody of common pathogen among baise adult respiratory tract infection ranked:ADV,MP,CPN.Patients whose MP or CPN IgM antibody was positive and with according clinical symptoms could be diagnosed with MP or CPN infection.
