Analysis of factors that affect treatment compliance with oral anti-retroviral agents and nursing intervention measures in patients with AIDS
10.3760/cma.j.issn.1003-9279.2010.04.018
- VernacularTitle:艾滋病患者服用抗病毒药物治疗非依从性的原因分析和护理干预对策
- Author:
Liu-Mei XU
1
;
Gui-Lin YANG
;
Hui WANG
;
Gui-Ying LI
;
Wei-Zhen LAI
;
Hui-Lan WANG
;
Bo-Ping ZHOU
Author Information
1. 深圳市第三人民医院
- Keywords:
Acguired immunodeficiency syndrome;
Antiviral agents;
Nursing research
- From:
Chinese Journal of Experimental and Clinical Virology
2010;24(4):292-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate factors that affect treatment compliance with oral antiretroviral agents and figure out the corresponding nursing intervention to improve treatment compliance of AIDS patients. Methods To study on treatment compliance with oral anti-retroviral agents and viral loads of 389 patients with AIDS before and after nursing intervention during the period of anti-retroviral treatment.Results Among 389 cases, 108 cases had non-compliance with anti-retroviral agents. The reasons for noncompliance mainly came from losing heart or depression to prospect of anti-retroviral therapy, deficiency in medical science, side effects, social discrimination, and bad self-control ability, and so on. Through health education and nursing intervention, the treatment compliance as well as efficacy of anti-retroviral therapy(percentage of viral load at undetectable level ) has been significantly improved compare with patients without the corresponding nursing intervention ( P＜ 0.001 ). Conclusions Health education and nursing intervention can significantly enhance treatment compliance and efficacy of anti-retroviral agents of patients with AIDS.
